Inflammation in psoriasis can lead to renal dysfunction by upregulating NADPH oxidases as well as inducible nitric oxide synthase (Al-Harbi et al., 2017a), and it has also been confirmed to induce hepatic inflammation, resulting in protein and lipid metabolism disorders through interleukin (IL)-17 RC/NF-κB signaling (Al-Harbi et al., 2017b). Here, NFKB1 is linked to psoriasis.