As is known to all, the AP’s development process is related to apoptosis and necrosis of pancreatic acinar cells, the MAPK signaling pathway and Apoptosis signaling pathway were enriched by apoptosis-related proteins such as AKT1, CASP3, FOS, etc. Our molecular docking results showed that a high overall score existed in MAPK1 (ERK1/2) and FOS (c-Fos) when docking with 11 key components, which suggested that they may play an essential role in QYD against AP. The gene discussed is MAPK3; the disease is alkaline phosphatase measurement.