IL1B and Dravet syndrome: Similarly, when control and DS brain sections of HP and SFG were stained for hepcidin and IL-6, there was less IL-6 visible in the control brain (Figure 5I), whereas there was a higher co-localization in the granule cells of HP in DS subjects (Figures 5J–L) suggestive of hepcidin and proinflammatory cytokines (IL-1β and IL-6) being involved in host defense during neuroinflammation.