Moreover, as in WT mice, infection with H3N2 IAV did not further significantly increase microglial density in the hippocampus of infected APP/PS1 mice compared to non-infected APP/PS1 mice (Δ 5%, p = 0.71), [Two-way ANOVA FInfection (1, 8) = 0.0018, p = 0.96]. This evidence concerns the gene APP and infection.