Taken together these results revealed that basal synaptic transmission, as well as short-term synaptic plasticity in the hippocampal CA1 sub-region, were not affected in the AD mouse model at 6 months of age, and furthermore that also IAV infection did not lead to long-term alterations in WT or APP/PS1 mice (Figures 4A,B). Here, APP is linked to Alzheimer disease.