PRKN and Parkinson disease: Several PD-causing genes such as α-synuclein (SNCA), parkin (PARK2), Leucine-rich repeat kinase 2 (LRRK2), DJ-1 (PARK7) and PTEN-induced kinase 1 (PINK1) have been implicated in the pathogenesis of PD and have contributed to the creation of various genetic animal models (Lesage et al., 2020; Tolosa et al., 2020).