SNCA and synucleinopathy: Synucleinopathies are a group of neurodegenerative disorders that share a pathological hallmark of intracellular inclusions, composed largely of the α-synuclein protein (SNCA), known as Lewy bodies (LBs) and Lewy-related neurites (Spillantini et al., 1997; Spillantini, 1999; Galvin et al., 2001; Jellinger, 2003; Marti et al., 2003).