Genes annotated for regulation of cell proliferation were the only functional group that was frequently annotated among AS genes in both clinical conditions, although the sets of genes in each contrast are different, with the exception of NF2. In the case of this gene group, most splicing changes occurred in SE and AF events, except for an A5 event detected in the control contrast (STAT6) and an A3 event in patient (ITSN1). This evidence concerns the gene STAT6 and atrial fibrillation.