The results showed that a high expression level of lncRNA KCNQ1OT1 in cancer tissue correlated with poor OS in patients with overall tumors (pooled HR=1.80, 95% CI: 1.17-2.78; P=0.008) (Fig. 1A) with a random-effects model (I2=80%, P<0.001). This evidence concerns the gene KCNQ1OT1 and cancer.