Subsequently, we examined the effect of ABCC5 on the migration of prostate cancer cells, and the results of scratch and transwell migration assays showed that knockdown of ABCC5 significantly reduced the migration of prostate cancer cells, while overexpression of ABCC5 significantly enhanced the migration of prostate cancer cells (Figure 3F-H, Supplementary Figure 2A-B). The gene discussed is ABCC5; the disease is Familial prostate cancer.