AUTS2 and autism: It has been demonstrated that CK2 interacts with AUTS2, a component of the PRC1.5 complex.232 AUTS2, encoded by the autism susceptibility candidate 2 gene (AUTS2) is a nuclear protein expressed in the developing cerebral cortex and cerebellum regions often affected by neuropathological alterations in autism, and its mutations or disruption alter the transcriptional programs associated with normal brain development.