CSNK2A1 and type 2 diabetes mellitus: In fact, the analysis of human microarray data of pancreatic β-cell enriched samples from T2DM patients and healthy donors revealed a significant rise of ∼1.2-fold in CK2α gene (CSNK2A1) expression in T2DM subjects, compared to nondiabetic individuals.262 In addition, the comparison of liver tissues between obese T2DM mice and control mice aged of 16 and 32 weeks highlighted that CSNK2A1 expression and CK2α protein level are strikingly increased in diabetic animals.