Considering that the uptake of bendamustine into lymphoma cells is thought to be through human organic cation transporter 1 (OCT1) and human organic anion transporter 3 (OAT3) [29, 30], the difference in drug transporters between anti-pyrimidine drugs and bendamustine might have caused this discrepancy. The gene discussed is SLC22A8; the disease is lymphoma.