The cardinal role of core fucosylation in regulating neuronal functions is highlighted in a study by Fukuda et al., where mice lacking α1,6-fucosyltransferase (Fut8—an enzyme responsible for the attachment of a fucose residue to the core pentasaccharide characteristic of N-glycans) display behavioural impairments and schizophrenia-like behaviour [78]. Here, FUT8 is linked to schizophrenia.