SOX5 and colorectal carcinoma: To confirmed whether miR-194-5p regulated SOX5 expression, we detected expression levels of SOX5 in HT29 and SW480 cells after transfection of miR-194-5p-mimics, qRT-PCR and analysis revealed that miR-194-5p overexpression significantly inhibited the expression of SOX5 in CRC cells (Fig. 6D).