A gene found in several of these groups was POLR3D, a DNA-directed RNA III polymerase subunit, which is lost (hom del, loss of mRNA or protein expression) in about 8% breast cancer cases, however, its loss, in patients for which at least on of the DDR gene is lost , results in significantly better disease-free survival (\documentclass[12pt]{minimal}\usepackage{amsmath}\usepackage{wasysym}\usepackage{amsfonts}\usepackage{amssymb}\usepackage{amsbsy}\usepackage{mathrsfs}\usepackage{upgreek}\setlength{\oddsidemargin}{-69pt}\begin{document}$$p=0.0278$$\end{document}p=0.0278), as shown in Fig. 8. The gene discussed is POLR3D; the disease is breast cancer.