Furthermore, the gene expression of α‐smooth muscle actin (αSma) and transforming growth factor‐1β (Tgf‐β1), which encode proteins involved in hepatic fibrosis, was lower in HFD‐fed p62‐KO‐Ex mice, but the expression of collagen type 1α (Colla1) was similar in the two groups. Here, ACTA1 is linked to Hepatic fibrosis.