HNF1A and colorectal carcinoma: Cell growth was then calculated to evaluate the proliferative properties of the cells, which revealed significant differences in cell numbers between the wild-type (WT; cells without transfection) or negative control (NC; cells with transfection of negative control) groups and the HNF1A siRNA (siHNF1A; cells with transfection of the siHNF1A) group for both CRC cell lines (P < 0.05; Fig. 2d).