RUNX1 and chronic myelogenous leukemia, BCR-ABL1 positive: In the CML-BC samples, mutations were frequently found in the driver genes implicated in myeloid malignancies, including RUNX1, ABL1, ASXL1, BCOR/BCORL1, TP53, and WT1 (Fig. 1c and Supplementary Fig. 1e).