To understand the molecular mechanism of N4BP1 in the regulation of neutrophil infiltration, we examined the mRNA level of several key genes involved in inflammation including TNFa, IL-23, IL-17, CXCL1, CCL20, S100A8, and S100A9 in psoriasis skin from N4BP1 KO and WT mice. The gene discussed is IL17A; the disease is psoriasis.