Lastly, evaluating a tissue microarray (TMA) from a cohort of 482 salivary gland cancer patients (424 evaluable for IHC) representing the Aci (n = 76), AdCC (n = 176), MEC (n = 80), and SDC (n = 92) subtypes, we show that the LMW-E and CDK5 concordant expression occurs in 70% of all patients and is strongly predictive of recurrence free survival. This evidence concerns the gene CDK5 and salivary gland cancer.