CCNE1 and salivary gland cancer: In this study, we describe a novel mouse model of salivary gland cancer initiation (MMTV-LMW-E; p53+/; CDK2−/−) driven by the low-molecular-weight forms of cyclin E (LMW-E), the oncogenic properties of which have been reported by our group in both preclinical models and in patient samples, reviewed in ref. 12.