NRP2 and posterior cortical atrophy: Analysis of RNA-seq data from metastatic castration-resistant PCa (CRPC) patients revealed that NRP2 expression in bone is significantly higher as compared to the other visceral and soft tissue metastatic sites (https://www.cbioportal.org/study/summary?id=prad_su2c_2019) (Fig. 1b).21 These results therefore indicated a potential role of NRP-2 in bone metastatic PCa.