In our study, we also observed that other TFH lymphomas and AITL were mainly classified as PTCL-TBX21 based on IHC staining; these also exhibited RHOA, IDH2, and DNMT3A, which are included in the category of epigenetic modulators (Fig. 4). This evidence concerns the gene IDH2 and mature T-cell and NK-cell non-Hodgkin lymphoma.