Consistently, quantitative PCR (qPCR) analysis of 19 CRC specimen pairs (primary tumour and corresponding normal tissues) acquired from the Xijing Hospital of Digestive Diseases revealed that the relative transcription levels of PUS7 were dramatically upregulated in CRC tissues in contrast to those in non-malignant controls (Fig. 1i). This evidence concerns the gene PUS7 and colorectal carcinoma.