In the striatum, non-supplemented HD mice showed an increase in Kmo transcripts compared with WT mice (p = 0.0447) and, in the cortex, iron-supplemented HD mice had increased levels of Kmo transcripts compared with non-supplemented HD mice (p = 0.007) and iron-supplemented WT mice (p = 0.0015). The gene discussed is KMO; the disease is Huntington disease.