Finally, by higher resolution tissue staining of TNC‐high tumors, we noticed a punctate CXCL12 signal in the stroma, importantly colocalizing with TNC and CD8 TIL, altogether suggesting that the described chemoretention by TNC/CXCL12 might be relevant for tethering CD8 TIL in the tumor stroma (Appendix Fig S3L). The gene discussed is CXCL12; the disease is neoplasm.