This is supported by published work showing that blocking the TLR4/TNC interaction increased the anti‐PD‐L1 effects on metastasis inhibition (Deligne et al,2020) and that combined treatment of anti‐PD‐L1 with AMD increased TIL infiltration reducing tumor growth in a pancreatic tumor model (Feig et al,2013). Here, TLR4 is linked to pancreatic neoplasm.