IBSP and colorectal carcinoma: Finally, the mechanisms how IBSP is involved in cell proliferation, apoptosis, cell cycle, invasion, migration, and EMT might be the abnormal activation of Fyn/β‐catenin signaling pathway, the detailed mechanism of IBSP and Fyn/β‐catenin signaling pathway involved in CRC progression will be clarified in the follow‐up research.