Different clinical trials of gene replacement therapy for inner ear and central hearing disorders—caused by biallelic recessive and loss‐of‐function dominant mutations—have broadened the horizons towards using such a strategy in the treatment of auditory and/or vestibular conditions; for instance, several gene therapy trials including those for the autosomal recessive gene MYO7A causing Usher syndrome are being undertaken.110. This evidence concerns the gene MYO7A and Usher syndrome.