We explored expression of different cancer-related lncRNAs in lung cancer cells after sevoflurane inducement, namely PCAT6, Urothelial cancer associated 1 (UCA1), Small Nucleolar RNA Host Gene 1 (SNHG1), colon cancer-associated transcript 2 (CCAT2), and found that PCAT6 was the only one significantly suppressed after sevoflurane administration. The gene discussed is PCAT6; the disease is lung cancer.