We demonstrated that LINC00987 and A2M could be consistently regarded as protective factors in BRCA, kidney renal clear cell carcinoma, LUAD, sarcoma (SARC), cutaneous skin melanoma (SKCM), and UCEC; however, both were revealed to be risk factors for mesothelioma (MESO; Figures 9E,F). Here, A2M is linked to mesothelioma.