Somatic LKB1 mutations have been implicated in a spectrum of malignancies, including lung cancer, cervical cancer, breast cancer, malignant melanoma, non-small cell lung carcinomas, and acute myeloid leukemia (AML) (Guldberg et al., 1999; Fenton et al., 2006; Ji et al., 2007; Matsumoto et al., 2007; Wingo et al., 2009; Marinaccio et al., 2020). Here, STK11 is linked to acute myeloid leukemia.