ESR1 and cancer: Known cancer-related genes from CGC, such as MYD88 (Figures 2A, D), DDX10 (Figures 2B, F), MLLT6 (Figure 2D), BCL10 (Figure 2F), and KAT6A (Figure 2F) also interacted with ESR1. The expression of MYD88 could be modulated in a single nucleotide polymorphism (SNP)- and estrogen-dependent fashion (19).