IL2 and neoplasm: Similar to IL-2 structure, rIL-2 (recombinant IL-2) generated by genetic technology can raise T-cell propagation and differentiation, increase the NK cell activity, activate the production of cytotoxic T lymphocyte (CTL), stimulate the generation of tumor-infiltrating lymphocyte (TIL) and lymphokine-activated killer (LAK) cell, activate B-cell proliferation, differentiation, and antibody secretion, and induce the interferon (IFN)-c and other cytokines production (150).