IFNG and melanoma: In the B16F10 mouse model, poly (I:C) liposomes can inhibit melanoma growth in a dose-dependent manner, accompanied by increasing numbers of TRP-2-tetramer(+)CD8(+) cells in lymph nodes, maturation of DCs and increasing numbers of TRP1-specific IFN-γ-producing cells in lymph nodes and the spleen (38).