IARS1 and neoplasm: Through correlation analysis, we found that the IRS was significantly positively correlated with tumor purity (r = 0.45, P <0.01), the hormone a score (r = 0.16, P <0.01), the hormone b score (r = 0.12, P <0.01) and the proliferation score (r = 0.11, P <0.01) and significantly negatively associated with the EMT score (r = -0.26, P <0.01) and the apoptosis score (r = -0.20, P <0.01) (Figure 7A and Supplemental Table S3).