Although the pathophysiology of psoriasis is complex and to a certain degree arguable, several important pathways are defined to play role in the progression of psoriatic inflammation, namely, activated nuclear factor kappa B (NF-κB), Janus kinase/signal transducer and activator of transcription (JAK/STAT), phosphoinositide 3-kinase/protein kinase B (PI3K/AKT) and mitogen activate protein kinase (MAPK) signaling (Engelman et al., 2006; Wolf et al., 2010; Andres et al., 2013; Schwartz et al., 2017; Li et al., 2019; Liang et al., 2019; Sakurai et al., 2019). Here, NFKB1 is linked to psoriasis.