The study explored whether (i) upregulating 14-3-3γ via Cap pretreatment contributed to autophagy via the AMPK-mTOR/ULK1 pathway against LPS-induced sepsis to myocardial injury (ii) Cap protected cardiomyocytes from LPS-induced inflammation, excessive oxidative stress, and mitochondrial dysfunction. The gene discussed is MTOR; the disease is Sepsis.