Compared with the DOX-HF group, glycogen content increased in aFGF-NP and aFGF + UTMD (p < 0.05), the quantitative analysis of glycogen content (Figure 4E) showed that aFGF-NP + UTMD could significantly improve the disturbance of glucose metabolism in doxorubicin-induced heart failure (p < 0.05). Here, FGF1 is linked to heart failure.