Genotype frequencies of both polymorphisms fit the Hardy-Weinberg equilibrium in AD patients (p = 0.05 and χ2 = 4.13 for MMP2; p = 0.59 and χ2 = 0.29 for MMP3) as well as in controls (p = 0.56 and χ2 = 0.33 for MMP2; p = 0.17 and χ2 = 1.93 for MMP3). The gene discussed is MMP2; the disease is Alzheimer disease.