C3 and infection: Although there was no difference in viral titers recovered from the cornea of WT and C3 KO mice at days 3 or 7 post infection (pi) (Fig. 1B), there was a significant increase in the amount of infectious virus recovered from the trigeminal ganglia (TG) of C3 KO mice compared to that recovered from WT TG at day 7 but not day 3 pi (Fig. 1C).