APOA5 and metabolic syndrome: In both models, most SNPs showed the association, especially two variations of the APOA5 gene: rs2266788, MetS model: [OR = 1.3, p = 3.66E − 07], HTg-MetS model: [OR = 1.4, p = 2.32E − 11] and rs651821, MetS model: [OR = 1.3, p = 2.86E − 07], HTg-MetS model: [OR: 1.4, p = 3.63E − 11] (Tables 3 and 4).