Currently, diabetes research shows that the actual cause of developing T2D seems to be strongly correlated with pancreatic \documentclass[12pt]{minimal}\usepackage{amsmath}\usepackage{wasysym}\usepackage{amsfonts}\usepackage{amssymb}\usepackage{amsbsy}\usepackage{mathrsfs}\usepackage{upgreek}\setlength{\oddsidemargin}{-69pt}\begin{document}$$\beta $$\end{document}β-cells; however it has long been assumed that insulin resistance is the major risk component. Here, INS is linked to diabetes mellitus.