Among these interactors, TRAF2 influences mitochondrial apoptosis of ccRCC [35]; KLK6’s expression is negatively associated with renal carcinoma grades [36]; higher HLA-E mRNA level predicts better prognosis of ccRCC patients [37]; FAS can be potentially regarded as a biomarker for predicting survival of renal cancer patients who have received nephrectomy [38]. The gene discussed is FAS; the disease is nonpapillary renal cell carcinoma.