Inhibition of the Wnt/β-catenin pathway by ART prevents NSCLC tumorigenesis (via Cyclin D1 production) and epithelial-mesenchymal transition (via E-cadherin production) and also reduces cell migration (via matrix metalloproteinase production), again displaying the value of using ART to reduce tumour proliferation and metastasis [70]. This evidence concerns the gene CCND1 and neoplasm.