Similarly, Fgfr1 levels were 4.5-fold up-regulated in pigmented versus non-pigmented mouse melanocytes (Student’s t-test P = 1.32 x 10−2), and 111.6-fold up-regulated in pigmented mouse melanoma cells, relative to non-pigmented such cells (Student’s t-test P = 1.47 x 10−2; Fig 7C). The gene discussed is FGFR1; the disease is melanoma.