Overall, vaccination coverage among U.S.-born adults was significantly higherthan that of foreign-born adults, including influenza vaccination (aged≥19 years), pneumococcal vaccination (all ages), tetanus vaccination(all ages), Tdap vaccination (all ages), hepatitis B vaccination (aged≥19 years and 19–49 years and travelers aged ≥19years), herpes zoster vaccination (all ages), and HPV vaccination amongfemales aged 19–26 years. The gene discussed is PPIB; the disease is Hepatitis.