Besides PanIN lesions, ARID1A deficiency could also facilitate intraductal papillary mucinous neoplasm (IPMN) formation through multiple pathways, including MYC-mediated protein synthesis (Wang et al., 2019) and SOX9/mTOR pathway (Kimura et al., 2018). The gene discussed is SOX9; the disease is pancreatic intraductal papillary-mucinous neoplasm.