Using a cerebral palsy rat model, Wen (2020) discovered that the overexpression of miR-135b can downregulate S100B, which helps to inactivate the signal transducer and activator of transcription-3 (STAT3) pathway, and promotes neural stem cell (NSC) differentiation and proliferation but inhibits NSC apoptosis [35]. The gene discussed is STAT3; the disease is cerebral palsy.