Remarkably, as shown in Fig. 4, BMP4, PHLDA1, and GJB5 expression levels were significantly upregulated in the G12A-, G12D-, G12V- transfected cells, compared those in the WT-transfected cells, suggesting that these genes can be added to the list of candidates of KRAS G12A, G12D, or G12V target genes in CRC. Here, BMP4 is linked to colorectal carcinoma.