Compared with the MI group, the density of the TH positive (15,411 ± 8,955 vs. 38,180 ± 18725 μm2/mm2, p = 0.023), GAP43 positive (20,436 ± 7,497 vs. 40,870 ± 3701 μm2/mm2, p < 0.001) and NF positive (74,473 ± 14,141 vs. 103,966 ± 12313 μm2/mm2, p = 0.003) nerves in the MI+LLVNS group was remarkably reduced. The gene discussed is GAP43; the disease is myocardial infarction.