There were also no significant differences in age, BMI, menstrual status, lesion position, LN stage, histological type, ER status, PR status, Ki67, BI-RADS, tumor shape, and color Doppler flow between the training and validation cohorts; however, differences in some clinicopathologic characteristics were observed in patients of these two cohorts owing to the spatial span of the different institutions, according to our study. This evidence concerns the gene MKI67 and neoplasm.