HSF1 and lip and oral cavity carcinoma: The present study sought to develop a QD-based (goat anti-mouse QD525nm-IgG and goat anti-mouse QD655nm-IgG) method for long-term dynamic observation of the physiological changes of heat shock protein 70 (HSP70) and heat shock factor 1 (HSF-1) in SCC-25 cells induced by heat shock and to explore strategies to influence the impact of activation of HSF-1 and the accumulation of HSP70 in oral cancer [102].